Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Histone Deacetylase Inhibitor II
The Histone Deacetylase Inhibitor II, also referenced under CAS 174664-65-4, controls the biological activity of Histone Deacetylase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ WRN Helicase Inhibitor, NSC 19630
The WRN Helicase Inhibitor, NSC 19630, also referenced under CAS 72835-26-8, controls the biological activity of WRN Helicase. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ MMP Substrate III, Fluorogenic
A specific fluorogenic resonance energy transfer (FRET) peptide substrate with an MMP cleavable Gly-Leu bond and EDANS/Dabcyl as fluorophore/quencher combination.
MilliporeSigma™ Calbiochem™ TGF-β RI Kinase Inhibitor II
TGF-β RI Kinase Inhibitor II, CAS 446859-33-2, is a cell-permeable, potent, reversible, ATP-competitive inhibitor of TGF-β R1 kinase (IC50 = 23 nM and 4 nM for ALK5 binding & auto-phosphorylation).
MilliporeSigma™ Calbiochem™ MIF Antagonist, ISO-1
The MIF Antagonist, ISO-1, also referenced under CAS 478336-92-4, controls the biological activity of MIF.
MilliporeSigma™ Calbiochem™ PARP Inhibitor IX, EB-47
The PARP Inhibitor IX, EB-47 controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Suramin, Sodium Salt
A reversible and competitive inhibitor of protein tyrosine phosphatases.
MilliporeSigma™ Calbiochem™ NF-κB Activation Inhibitor VII, CID-2858522
The NF-κB Activation Inhibitor VII, CID-2858522 controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Phloretin
A cell-permeable inhibtor of protein kinase C (IC50 = 20-50 μM).
MilliporeSigma™ Calbiochem™ 2-APB
A cell-permeable modulator of Ins(1,4,5)P3-induced Ca2+ release.
MilliporeSigma™ Calbiochem™ Quinacrine, Dihydrochloride
A non-specific phospholipase A2 (PLA2) inhibitor.
MilliporeSigma™ Calbiochem™ WP1130
A cell-permeable tyrphostin compound that acts as a partially selective deubiquitinase (DUB) inhibitor and suppresses JAK-Stat signaling pathway.
MilliporeSigma™ Calbiochem™ USP1-UAF1 Inhibitor, ML323
A cell-permeable, selective, potent, and reversible inhibitor of USP1-UAF1 deubiquitinase (IC50 = 76 nM in Ub-Rhodamine based assays). Does not disrupt USP1-UAF1 association.
MilliporeSigma™ Calbiochem™ SIRT1 Activator II
The SIRT1 Activator II, also referenced under CAS 374922-43-7, modulates the biological activity of SIRT1. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ PICK1 PDZ Domain Inhibitor, FSC231
The PICK1 PDZ Domain Inhibitor, FSC231 controls the biological activity of PICK1. This small molecule/inhibitor is primarily used for Neuroscience applications.